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Ampicillin and a fixed combination of erythromycin estolate-triple sulfonamide suspension proved equally effective in eradicating or ganisms and exudate in otitis media. Triple sulfonamide was not as effective as a number of other drugs tested for eliminating the pneu mococcus, and erythromycin estolate was not as effective as the fixed combination or ampicillin with Hemophilus influenzae.
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Howie et al. (1972) studied this question.
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