Why the study?
Do refined anticoagulation monitoring techniques improve blood loss and transfusion outcomes in patients undergoing cardiac surgery with cardiopulmonary bypass?
Population
Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB)
Comparison
Anticoagulation monitoring techniques vs Empiric protocols or unrefined monitoring
Design
Review
Authors
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Inconsistent evidence precludes practice changes in ACT monitoring; leaves open whether refined protocols reduce bleeding in cardiac surgery.
Do refined anticoagulation monitoring techniques improve blood loss and transfusion outcomes in patients undergoing cardiac surgery with cardiopulmonary bypass?
Current literature on anticoagulation monitoring during cardiopulmonary bypass is inconsistent, highlighting the need for more well-controlled studies to determine if refined monitoring techniques improve bleeding and transfusion outcomes.
Despotis et al. (1999) studied this question.
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