A brief account is given of various approaches to the individualization of drug dosage, including the use of pharmacodynamic markers, therapeutic monitoring of plasma drug concentrations, genotyping, computer-guided dosage using 'dashboards', and automatic closed-loop control of pharmacological action. The potential for linking the real patient to his or her 'virtual twin' through the application of physiologically-based pharmacokinetic modeling is also discussed.
No takes yet. Share an insight, caveat, or question.
Geoffrey T. Tucker (2016) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: