Key points are not available for this paper at this time.
Design
Preclinical
Hypothesis-generating for PVAT-targeted vascular therapies; leaves open translation to human disease.
PVAT exerts its anti-contractile effects through two distinct mechanisms: (1) by releasing a transferable relaxing factor which induces endothelium-dependent relaxation through NO release and subsequent K(Ca) channel activation, and (2) by an endothelium-independent mechanism involving H2O2 and subsequent activation of sGC.
No takes yet. Share an insight, caveat, or question.
Gao et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: