Literature review and meta-analysis reveals major comorbidities in primary headache disorders, highlighting the value of joint treatment approaches.
Some of the most relevant comorbidities of primary headache disorders - back pain, anxiety and depression, diabetes, ischemic heart disease and stroke - are among the most burdensome conditions, together with headache themselves, according to the GBD study. A joint treatment of headaches and of these comorbidities may positively impact on headache sufferers' health status and contribute to reduce the impact of a group of highly burdensome diseases.
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Caponnetto et al. (2021) studied this question.
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