Predictors of Device-Related Adverse Events in Patients with Intra-aortic Ballon Pump or Microaxial Flow Pump for Cardiogenic Shock

Device-related adverse events (DRAEs) are common with intra-aortic balloon pump (IABP) and microaxial flow pump (mAFP) in cardiogenic shock (CS), yet predictors of DRAEs are underrecognized.We performed a single-center, retrospective review of consecutive adults from 8/2021-8/2024 with CS and IABP or mAFP.Events were adjudicated as device-related if occurring during IABP/mAFP support or <72 hours of removal.DRAEs included bleeding, bacteremia, stroke/transient ischemic attack, vascular injury, heparin induced thrombocytopenia, and major hemolysis.Multivariable regression was performed to identify independent predictors of DRAEs.The study population (n=400) was predominantly male (71.5%) with stage D/E CS (53.7%).In total, 251 DRAEs were identified.Independent DRAE predictors included non-white race, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) exposure, outside hospital device placement, and >1 device, while IABP-only was protective.