Fair priority setting in gene-editing research: the accountability for reasonableness framework

With rapid scientific advancements in gene-editing technologies, we advocate using the Accountability for Reasonableness (A4R) framework to guide priority setting of gene-editing research, ensuring equitable, efficient, consistent, and accountable translation of these revolutionizing innovations into society. In this Comment article, M. J. Smits and colleagues propose applying the Accountability for Reasonableness (A4R) framework to guide fair, transparent, and ethically grounded priority setting in gene-editing research.