BackgroundTotal generalized variation (TGV) based CT iterative reconstruction algorithm has the ability to effectively suppress the staircase effects caused by the piecewise constant assumption of total variation regularization. By unrolling the model-based iterative reconstruction to networks, the deep unrolling approach can further improve image quality within a finite number of iterations by data-driven training. However, most deep unrolling approaches focus on unrolling the data fidelity term into deep neural networks, which limit the performance of the deep unrolling approach.ObjectiveTo address this issue, we unrolled both the data fidelity term and the TGV term to construct a novel low-dose CT reconstruction network, called TGV based deep unrolling approach (TGV-DU).MethodsThe Chambolle-Pock algorithm was employed to solve the TGV based CT iterative reconstruction problem to obtain a single-loop CT iterative reconstruction algorithm, which is easy to be unrolled to neural networks. In the proposed algorithm, the parameterized mapping that updates primal variables and dual variables across successive iterations was implemented by convolutional neural networks and was dynamically learned from big data.ResultsTo validate the effectiveness of our proposed algorithm, we perform the experiment on the "Low-Does CT Image and Projection Data" dataset. The results show that the proposed TGV-DU outperforms other state-of-the-art methods quantitatively and qualitatively.ConclusionsExperiments show that our proposed algorithm can effectively alleviate the piecewise smoothness while preserve more structural details.
Wu et al. (Thu,) studied this question.