Case report demonstrates treatment effects on coronary artery aneurysms in an infant with Kawasaki disease, suggesting complexities in IL-1's role.
An infant presented with macrophage activation syndrome as part of Kawasaki disease, and was first treated with canakinumab, followed by methylprednisolone and IVIG. Despite early treatment, giant coronary artery aneurysms developed transiently, questioning the singular role of IL-1 in KD.
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Netea et al. (2026) studied this question.
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