This research demonstrates enhanced synthesis of β-hydroxy esters in continuous processing compared to batch methods, highlighting practical implications for chemical synthesis.
Lithium diisopropylamide (LDA)-mediated aldol condensation is a fundamental method for the synthesis of β-hydroxy esters. This strategy was applied in our previous synthesis of the general cap structure of Chidamide...
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Guo et al. (2026) studied this question.
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