Cross-cultural adaptation, reliability and construct validity of the Arabic Scleroderma Assessment Questionnaire in Egyptian patients with systemic sclerosis

The Ar-SAQ is a reliable and valid instrument for assessing patient-reported disease status in Egyptian SSc patients and may serve as a foundation for further validation in other Arabic-speaking populations. Key Points • A culturally adapted Arabic version of the Scleroderma Assessment Questionnaire was developed following standardized cross-cultural adaptation guidelines. • The Arabic Scleroderma Assessment Questionnaire demonstrated good to excellent reliability and acceptable construct validity in Egyptian patients with systemic sclerosis. • This instrument provides a feasible patient-reported measure of disease status that may support clinical assessment and research in Arabic-speaking populations.