Key result
M-TEER effectively resolves hemolytic anemia caused by recurrent MR following prior surgical repair.
Why the study?
Does transcatheter mitral edge-to-edge repair (M-TEER) resolve hemolytic anemia in a patient with severe valvular mitral regurgitation after prior surgical mitral valve repair?
Case Report (n=1)
Does transcatheter mitral edge-to-edge repair (M-TEER) resolve hemolytic anemia in a patient with severe valvular mitral regurgitation after prior surgical mitral valve repair?
Transcatheter mitral edge-to-edge repair (M-TEER) may be a safe and effective option for managing hemolytic anemia due to recurrent valvular mitral regurgitation after prior surgical repair in patients at prohibitive surgical risk.
Answers are grounded in this paper and cite their sources.
May warrant M-TEER for hemolytic anemia from recurrent MR after surgical repair; hypothesis-generating pending larger studies.
BACKGROUND: Hemolytic anemia after surgical valve repair is rare but potentially life-threatening and has mostly commonly been described in the context of paravalvular regurgitation. CASE SUMMARY: A 78-year-old woman with prior surgical mitral valve (MV) repair presented with progressive dyspnea and severe hemolytic anemia. Echocardiography revealed severe eccentric, valvular mitral regurgitation (MR) caused by anterior leaflet prolapse with a high-velocity regurgitant jet striking the annuloplasty ring. The patient underwent transcatheter mitral edge-to-edge repair (M-TEER), achieving reduction of MR to mild and resolution of hemolysis. DISCUSSION: This case highlights hemolysis as a rare complication after surgical MV repair and the utility of M-TEER for patients at prohibitive surgical risk. TAKE-HOME MESSAGES: M-TEER may represent a safe and effective option for managing hemolytic anemia due to recurrent MR. Besides paravalvular regurgitation, valvular regurgitation in the context of prior surgical MV repair should be recognized as a potential cause of hemolytic anemia.
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Scheffler et al. (2026) conducted a case report in Hemolytic anemia and severe mitral regurgitation after surgical mitral valve repair (n=1). Transcatheter mitral edge-to-edge repair (M-TEER) was evaluated on Reduction of mitral regurgitation and resolution of hemolysis. Transcatheter mitral edge-to-edge repair successfully reduced severe mitral regurgitation to mild and resolved severe hemolytic anemia in a patient with prior surgical mitral valve repair.
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