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Systematic review reveals gastrointestinal symptoms and comorbidities in POTS patients, suggesting chronic health challenges.
Overall, 60% of POTS patients report concurrent gastrointestinal symptoms, with nausea being the most common. IBS affects 25% of patients with POTS. Notably, extra-intestinal comorbidities-primarily anxiety, chronic fatigue, migraines, depression, and fibromyalgia-are more prevalent than gastrointestinal conditions in this population.
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Kulin et al. (2026) studied this question.
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