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June 6, 2016American Journal of Respiratory and Critical Care MedicineOpen Access

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

Lonneke A. van Vught Brendon P. Scicluna Maryse A. Wiewel Arie J. Hoogendijk Peter M. C. Klein Klouwenberg Marek Franitza Mohammad R. Toliat Peter Nürnberg Olaf L. Cremer Janneke Horn Marcus J. Schultz Marc J. M. Bonten Tom van der Poll

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Abstract

Patients with HAP and CAP present with a largely similar host response at ICU admission.

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Vught et al. (2016) studied this question.

synapsesocial.com/papers/69da09259a6164e50fa3daf2 https://doi.org/10.1164/rccm.201602-0368oc

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Severe Sepsis and Septic ShockOriginal Research · 2013 · 3,993 citations
2Underlying Disorders and Their Impact on the Host Response to InfectionPrognostic Study · 2005 · 108 citations
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4Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice*Original Research · 2008 · 33 citations
5Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis*Original Research · 2004 · 28 citations

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