Population
Platelets and endothelial cells (in vitro/preclinical model)
Comparison
Platelet aggregation induced by physiological… vs Unstimulated platelets or absence of eptifibatide
Design
Preclinical
Authors
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PEAR1 may represent a novel platelet signaling target; leaves open its role in human thrombosis pending validation studies.
Identifies PEAR1 as a novel platelet receptor that signals secondary to alpha(IIb)beta(3)-mediated platelet-platelet contacts.
Nanda et al. (2005) studied this question.
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