Shows that Shexiang Tongxin Dripping Pills reduce myocardial reperfusion injury in mice via SOD/TNF-α/IL-6 signaling, suggesting benefits for integrative cardiovascular treatment.
STDP ameliorates MIRI in mice by inhibiting inflammatory responses and oxidative stress, primarily through modulation of the SOD/TNF-α/IL-6 pathway. Its cardioprotective effects include reducing apoptosis, inflammation, ROS, infarction size, and arrhythmias, while improving cardiac function and tissue repair. These findings elucidate a key mechanism for STDP and provide empirical support for its clinical use in MIRI, offering innovative perspectives for managing cardiovascular disorders with TCM and facilitating the integration of traditional and modern medicine.
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Du et al. (2025) studied this question.
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