July 24, 2009Open Access
View Full PaperActivated Cell Survival Cascade Protects Cardiomyocytes from Cell Death in Tako-Tsubo Cardiomyopathy
Structured PICO
P
Population
Cardiomyocytes in Tako-Tsubo Cardiomyopathy (TTC)
I
Intervention
PI3K/AKT signalling activation
O
Outcome
Protection from cell death and rapid regeneration
Activation of the PI3K/AKT cell survival cascade may explain the rapid regeneration and protection from cell death seen in Tako-Tsubo cardiomyopathy.
Abstract
PI3K/AKT signalling is activated in TTC. This activated cell survival cascade might protect cardiomyocytes from cell death and also contribute to rapid regeneration in TTC.