Why the study?
Should the Lamin A/C gene be included in genetic testing for patients with suspected ARVC?
Should the Lamin A/C gene be included in genetic testing for patients with suspected ARVC?
Answers are grounded in this paper and cite their sources.
Lamin A/C gene testing should be added to desmosomal gene panels for patients with suspected ARVC, especially when conduction disease is present on ECG.
Lamin A/C gene mutations can be found in severe forms of ARVC. Lamin A/C gene should be added to desmosomal genes when genetically testing patients with suspected ARVC, particularly when they also have ECG evidence for conduction disease.
No takes yet. Share an insight, caveat, or question.
Quarta et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: