Why the study?
Is microvascular dysfunction associated with higher odds of incident late-life depression?
Is microvascular dysfunction associated with higher odds of incident late-life depression?
Microvascular dysfunction is associated with higher odds of late-life depression, suggesting it may be a potential target for prevention and treatment.
Microvascular dysfunction may flag higher late-life depression risk; supports further trials to test causality and prevention strategies.
This meta-analysis shows that both the peripheral and cerebral forms of microvascular dysfunction are associated with higher odds of (incident) late-life depression. This finding may have clinical implications because microvascular dysfunction might provide a potential target for the prevention and treatment of depression.
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Agtmaal et al. (2017) studied this question.
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