March 30, 2023Journal of the American Society of Nephrology75 citationsOpen Access
Accuracy of GFR Estimating Equations in Patients with Discordances between Creatinine and Cystatin C-Based Estimations
Structured PICO
Does the combined eGFR cr-cys equation improve accuracy compared to eGFR cr or eGFR cys alone in patients with discordant estimations?
P
Population
Patients with discordances between creatinine and cystatin C-based GFR estimations
I
Intervention
Combined creatinine-cystatin C GFR estimating equation (eGFR cr-cys)
C
Comparator
Creatinine-based (eGFR cr) or cystatin C-based (eGFR cys) estimating equations alone
O
Outcome
Accuracy of GFR estimationsurrogate
In clinical practice, when creatinine and cystatin C-based eGFR estimates are highly discordant, the combined eGFR cr-cys equation provides the most accurate estimation of renal function.
Abstract
When eGFR cr and eGFR cys are highly discordant in clinical practice, eGFR cr-cys is more accurate than either eGFR cr or eGFR cys .
Cite This Study
Fu et al. (Thu,) studied this question.