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May 21, 2021SHILAP Revista de lepidopterologíaOpen Access

Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis

Yiqiang Hu Ranyang Tao Lang Chen Yuan Xiong Hang Xue Liangcong Hu Chenchen Yan Xudong Xie Ze Lin Adriana C. Panayi Bobin Mi Guohui Liu

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Abstract

PGZ-Exos accelerated diabetic wound healing by promoting the angiogenic function of HUVECs through activation of the PI3K/AKT/eNOS pathway. This offers a promising novel cell-free therapy for treating diabetic wound healing.

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Hu et al. (2021) studied this question.

synapsesocial.com/papers/69da45d7c4712b0965a3c2a6 https://doi.org/10.1186/s12951-021-00894-5

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Effective Wound Healing Enabled by Discrete Alternative Electric Fields from Wearable NanogeneratorsOriginal Research · 2018 · 400 citations
2Efficient Angiogenesis-Based Diabetic Wound Healing/Skin Reconstruction through Bioactive Antibacterial Adhesive Ultraviolet Shielding Nanodressing with Exosome ReleaseOriginal Research · 2019 · 551 citations
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4Promoting Angiogenesis in Oxidative Diabetic Wound Microenvironment Using a Nanozyme-Reinforced Self-Protecting HydrogelOriginal Research · 2019 · 344 citations
5The Role of Oxidative Stress and Antioxidants in Diabetic Wound HealingOriginal Research · 2021 · 764 citations

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