Narrative review outlines diagnostic and research applications of immunohistochemistry across diseased tissues, highlighting its utility in identifying tumor antigens for cancer detection.
Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease. IHC is widely used for diagnosis of cancers; specific tumor antigens are expressed de novo or up-regulated in certain cancers. This article deals with the various applications of IHC in diagnosis of diseases, with IHC playing an important role in diagnostic and research laboratories.
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Duraiyan et al. (2012) studied this question.
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