Does the absence of LGE at baseline predict left ventricular reverse remodeling at 2-year follow-up in patients with idiopathic dilated cardiomyopathy?
The absence of myocardial fibrosis (LGE) on baseline imaging strongly predicts left ventricular reverse remodeling at 2 years in patients with idiopathic dilated cardiomyopathy.
In patients with idiopathic dilated cardiomyopathy, the absence of LGE at baseline is a strong independent predictor of LV-RR at 2-year follow-up, irrespective of the initial clinical status and the severity of ventricular dilatation and dysfunction. The increase in LGE extent during follow-up was associated with progressive LV dysfunction.
Masci et al. (Sat,) studied this question.