⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

April 17, 2018Alimentary Pharmacology & TherapeuticsOpen Access

High body mass index is associated with increased risk of treatment failure and surgery in biologic‐treated patients with ulcerative colitis

Soumya Kurnool Nghia Nguyen J. Proudfoot Parambir S. Dulai Brigid S. Boland Niels Vande Casteele Elisabeth Evans Eduardo Grunvald Amir Zarrinpar William J. Sandborn Siddharth Singh

View Full Paper

Ask AI

Bookmark

Share

Abstract

BMI is independently associated with increased risk of treatment failure in biologic-treated patients with UC, independent of dosing regimen.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Kurnool et al. (2018) studied this question.

synapsesocial.com/papers/69daa20185037e71b2684383 https://doi.org/10.1111/apt.14665

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013Original Research · 2014 · 11,951 citations
2Impact of Obesity on the Management and Clinical Course of Patients with Inflammatory Bowel DiseaseCohort Study · 2015 · 177 citations
3Measures of Obesity and Risk of Crohnʼs Disease and Ulcerative ColitisCohort Study · 2015 · 166 citations
4Patient Factors That Increase Infliximab Clearance and Shorten Half-life in Inflammatory Bowel DiseaseCohort Study · 2014 · 291 citations
5Pharmacokinetics and Exposure–Efficacy Relationship of Adalimumab in Pediatric Patients with Moderate to Severe Crohnʼs DiseaseRCT · 2015 · 105 citations

Population pharmacokinetics-pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease2015
Predictors of dose escalation of adalimumab in a prospective cohort of Crohn’s disease patients2011
Increased Body Mass Index Is Associated with Earlier Time to Loss of Response to Infliximab in Patients with Inflammatory Bowel Disease2013
Maternal Obesity Is Associated With Adverse Pregnancy Outcomes in Inflammatory Bowel Disease: A Matched Electronic Health Record Cohort StudyAlimentary Pharmacology & Therapeutics · 2026
Meta‐Analysis: Potassium‐Competitive Acid Blockers Versus Proton Pump Inhibitors for Gastroprotection in Patients Receiving Antiplatelet TherapyAlimentary Pharmacology & Therapeutics · 2026

More from Alimentary Pharmacology & Therapeutics

More from University of California, San Diego

More from UC San Diego Health System

More from Southern California Clinical and Translational Science Institute