Why the study?
Does quantitative analysis of perfused lung volume using hybrid SPECT/CT correlate with disease severity in patients with CTEPH?
Does quantitative analysis of perfused lung volume using hybrid SPECT/CT correlate with disease severity in patients with CTEPH?
Quantitative analysis of perfusion SPECT provides a feasible imaging biomarker for assessing disease severity and potentially monitoring therapy in CTEPH.
May support SPECT perfusion quantification as a CTEPH severity biomarker; leaves open prospective validation before clinical use.
Quantitative analysis of perfusion defects at SPECT is feasible, provides a measure of disease severity, and correlates with established clinical parameters. Quantitation of perfusion SPECT may refine the diagnostic approach in CTEPH providing a quantitative imaging biomarker, for example, for therapy monitoring.
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Derlin et al. (2018) studied this question.
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