What question did this study set out to answer?

Evaluate the predictive capacity of a six-gene expression risk score for forecasting cancer recurrence in gastric cancer patients following surgical gastrectomy.

March 29, 2011Clinical Cancer ResearchOpen Access

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

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Authors

YCY. ChoiBeth Israel Deaconess Medical Center JLJae Yun LimThe University of Texas MD Anderson Cancer Center JCJae‐Ho CheongYonsei University

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Implication

Prognostic study reveals a six-gene risk score predicts post-gastrectomy relapse in gastric cancer patients, suggesting utility for personalized surveillance.

Key Points

Evaluate the predictive capacity of a six-gene expression risk score for forecasting cancer recurrence in gastric cancer patients following surgical gastrectomy.
Analyzed gene expression signatures to construct a prognostic risk score based on a six-gene panel.
Assessed recurrence outcomes in gastric cancer patients who underwent gastrectomy.
The six-gene risk score successfully prognosticates disease relapse after gastrectomy.
Gene expression stratification distinguishes patients at higher risk of recurrence from those with favorable postsurgical outcomes.

Cite This Study

Choi et al. (2011) studied this question.

synapsesocial.com/papers/69daa5c30f32475823a3d74e https://doi.org/10.1158/1078-0432.ccr-10-2180

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Implication

Prognostic study reveals a six-gene risk score predicts post-gastrectomy relapse in gastric cancer patients, suggesting utility for personalized surveillance.

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

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