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January 1, 1982Biometrika1,183 citations

A class of rank test procedures for censored survival data

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DHDavid P. HarringtonTFThomas R. Fleming

Key Points

  • The study aims to introduce a new class of rank test procedures suitable for right-censored survival data.
  • Developed linear rank statistics for k-sample problems with right-censored survival data.
  • Established asymptotic normality of the test statistics and evaluated relative efficiencies.
  • Presented distributions corresponding to the rank statistics for optimal alternative detection.
  • New test procedures show improved statistical efficiency under specified alternatives.
  • Asymptotic normality is confirmed under the null hypothesis for all proposed methods.
  • Monte Carlo results demonstrate robust performance in small sample scenarios.

Abstract

SUMMARY A class of linear rank statistics is proposed for the k-sample problem with rightcensored survival data. The class contains as special cases the log rank test (Mantel, 1966; Cox, 1972) and a test essentially equivalent to Peto & Peto's (1972) generalization of the Wilcoxon test. Martingale theory is used to establish asymptotic normality of test statistics under the null hypotheses considered, and to derive expressions for asymptotic relative efficiencies under contiguous sequences of alternative hypotheses. A class of distributions is presented which corresponds to the class of rank statistics in the sense that for each distribution there is a statistic with some optimal properties for detecting location alternatives from that distribution. Some Monte Carlo results are displayed which present small sample behaviour.

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Cite This Study

Harrington et al. (1982) studied this question.

synapsesocial.com/papers/69daa91efed504aaed8358fchttps://doi.org/10.1093/biomet/69.3.553
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