Why the study?
Does the use of Vitamin K Antagonists (VKAs) affect the frequency of cognitive impairment in geriatric patients?
Does the use of Vitamin K Antagonists (VKAs) affect the frequency of cognitive impairment in geriatric patients?
This pilot study suggests a potential association between VKA use, particularly fluindione, and cognitive impairment in geriatric patients.
May warrant caution with fluindione in geriatric patients; leaves open causality and requires prospective confirmation.
We found more frequent cognitive impairment associated with the use of VKAs, specifically fluindione, among geriatric patients.
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Annweiler et al. (2014) studied this question.
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