Currently Available Large Language Models Do Not Provide Musculoskeletal Treatment Recommendations That Are Concordant With Evidence‐Based Clinical Practice Guidelines

Although leading LLMs generally provide recommendations concordant with CPGs, a substantial error rate exists, and the proportion of recommendations that do not align with these CPGs suggests that LLMs are not trustworthy clinical support tools at this time. Each off-the-shelf, closed-source LLM has strengths and weaknesses. Future research should evaluate and compare multiple LLMs to avoid bias associated with narrow evaluation of few models as observed in the current literature.