April 27, 2017Radiology
T1 and T2 Mapping in Recognition of Early Cardiac Involvement in Systemic Sarcoidosis
Why the study?
Does quantitative tissue characterization with T1 and T2 mapping improve the recognition of early cardiac involvement in patients with systemic sarcoidosis?
Population
53 consecutive patients with a biopsy-proven extracardiac diagnosis of systemic sarcoidosis and 36…
Comparison
Cardiovascular magnetic resonance imaging with… vs Standard diagnostic criteria
Design
Cohort
Follow-up
mean 144 days ± 35 (for follow-up substudy)
Authors
Discussion
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Member takes
Implication
T1/T2 mapping may aid cardiac sarcoidosis detection; hypothesis-generating and should not yet change practice.
Structured PICO
Does quantitative tissue characterization with T1 and T2 mapping improve the recognition of early cardiac involvement in patients with systemic sarcoidosis?
P
Population
53 consecutive patients with a biopsy-proven extracardiac diagnosis of systemic sarcoidosis (21 men; median age 45 years) and 36 normotensive previously healthy control subjects (14 men; median age 43 years).
I
Intervention
Cardiovascular magnetic resonance imaging with quantitative tissue characterization using T1 and T2 mapping
C
Comparator
Standard diagnostic criteria
O
Outcome
Discriminatory accuracy for separation between healthy control subjects and patients with systemic sarcoidosissurrogate
T1 and T2 mapping by cardiovascular magnetic resonance imaging provides high discriminatory accuracy for the noninvasive recognition of cardiac involvement and tracks inflammatory activity in systemic sarcoidosis.
Cite This Study
Püntmann et al. (2017) studied this question.