August 4, 2016SHILAP Revista de lepidopterología195 citationsOpen Access
Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies
Structured PICO
Does long-term low-dose aspirin increase the risk of major bleeding in real-world settings?
P
Population
Patients in real-world settings receiving low-dose aspirin for prevention of cardiovascular events
I
Intervention
Long-term low-dose aspirin
O
Outcome
Major bleedingsafety
Real-world observational data confirms that the major bleeding risk associated with long-term low-dose aspirin is similar to the risk reported in randomized clinical trials.
Abstract
The risks of major bleeding with low-dose aspirin in real-world settings are of a similar magnitude to those reported in randomized trials. These data will help inform clinical judgements regarding the use of low-dose aspirin in prevention of cardiovascular events.