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May 1, 1995Synthetic Communications

A Common Strategy for the Synthesis of (+)-Hepialone and (±)-α-Lipoic Acid

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Abstract

A common method starting from a substituted aromatic system is presented for the synthesis of (+)-Hepialone and (&)-α-lipoic acid.

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Cite This Study

Rao et al. (1995) studied this question.

synapsesocial.com/papers/69dab6d237b5141e3ba3c4dc https://doi.org/10.1080/00397919508011765

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Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1An enantioselective synthesis of R-(+)-α-lipoic acidOriginal Research · 1990 · 16 citations
2On the scope of asymmetric nitrile oxide cycloadditions with Oppolzer's chiral sultam. Total syntheses of (+)-hepialone, (-)-(1R,3R,5S)-1,3-dimethyl-2,9-dioxabicyclo[3.3.1]nonane, and (-)-(1S)-7,7-dimethyl-6,8-dioxabicyclo[3.2.1]octaneOriginal Research · 1990 · 122 citations
3Chemistry and Biochemistry of α‐Lipoic AcidOriginal Research · 1965 · 44 citations
4Synthesis of 1,3-diol synthons from epoxy aromatic precursors: an approach to the construction of polyacetate-derived natural productsOriginal Research · 1991 · 91 citations