Fig. 1. Flow chart showing study selection process.
Fig. 2. Effect of omega-3 fatty acid on cardiovascular mortality. AREDS2: Age-Related Eye Disease Study 2; ASCEND: A Study of Cardiovascular Events in Diabetes; CI: confidence interval; DHA: Docosahexaenoic acid; DO IT: The Diet and Omega-3 Intervention Trial; EPA: Eicosapentaenoic acid; FA: fatty acid; FAAT: Fatty Acid Antiarrhythmia Trial; GISSI-P: Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Prevenzione; GISSI-HF: Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Heart Failure; HARP: Heart Attach Research Program; JELIS: Japan EPA Lipid Intervention Study; OFAMI: Omacor Following Acute Myocardial Infarction; ORIGIN: Outcome Reduction with an Initial Glargine Intervention; OMEMI: Omega-3 fatty acids in Elderly with Myocardial Infarction; REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial; SOFA: Study on Omega-3 Fatty Acids and Ventricular Arrhythmia Trial; SU.FOL.OM3: Supplémentation en Folates et Omega-3; STRENGTH: Long-Term Outcomes Study to Assess Statin Residual Risk with Epanova in High Cardiovascular Risk Patients with Hypertriglyceridemia; TG: triglycerides; VITAL: Vitamin D and Omega-3 Trial.
Fig. 3. Effect of omega-3 fatty acid on non-fatal myocardial infarction. AREDS2: Age-Related Eye Disease Study 2; ASCEND: A Study of Cardiovascular Events in Diabetes; CI: confidence interval; DHA: Docosahexaenoic acid; EPA: Eicosapentaenoic acid; FA: fatty acid; FORWARD: Randomized Trial to Assess Efficacy of PUFA for the Maintenance of Sinus Rhythm in Persistent Atrial Fibrillation Fish Oil Research with omega-3 for Atrial Fibrillation Recurrence Delaying; GISSI-P: Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Prevenzione; GISSI-HF: Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Heart Failure; HARP: Heart Attach Research Program; JELIS: Japan EPA Lipid Intervention Study; ORIGIN: Outcome Reduction with an Initial Glargine Intervention; OMEMI: Omega-3 fatty acids in Elderly with Myocardial Infarction; REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial; SOFA: Study on Omega-3 Fatty Acids and Ventricular Arrhythmia Trial; SU.FOL.OM3: Supplémentation en Folates et Omega-3; STRENGTH: Long-Term Outcomes Study to Assess Statin Residual Risk with Epanova in High Cardiovascular Risk Patients with…
Fig. 4. Effect of omega-3 fatty acid on coronary heart disease events. AREDS2: Age-Related Eye Disease Study 2; ASCEND: A Study of Cardiovascular Events in Diabetes; CI: confidence interval; DHA: Docosahexaenoic acid; DO IT: The Diet and Omega-3 Intervention Trial; EPE-A: Ethyl-eicosapentanoic Acid; EPA: Eicosapentaenoic acid; FORWARD: Randomized Trial to Assess Efficacy of PUFA for the Maintenance of Sinus Rhythm in Persistent Atrial Fibrillation Fish Oil Research with omega-3 for Atrial Fibrillation Recurrence Delaying; FA: fatty acid; FOSTAR: Fish oil in osteoarthritis; GISSI-P: Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Prevenzione; GISSI-HF: Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico-Heart Failure; HARP: Heart Attach Research Program; JELIS: Japan EPA Lipid Intervention Study; LDL-C: Low-density lipoprotein-cholesterol; OFAMI: Omacor Following Acute Myocardial Infarction; ORIGIN: Outcome Reduction with an Initial Glargine Intervention; OMEMI: Omega-3 fatty acids in Elderly with Myocardial Infarction; REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial; SHOT: Shunt Occlusion Trial; SCIMO: Study…
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