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January 1, 2014Cellular Physiology and BiochemistryOpen Access

Akt2 Mediates TGF-�1-Induced Epithelial to Mesenchymal Transition by Deactivating GSK3�/Snail Signaling Pathway in Renal Tubular Epithelial Cells

Aiping Lan Yongfen Qi Jie Du

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Abstract

These findings revealed that knockdown of Akt2 antagonized TGF-β1-induced EMT by inhibiting GSK3β/Snail signaling pathway.

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Lan et al. (2014) studied this question.

synapsesocial.com/papers/69dad86478a3e0e28868484a https://doi.org/10.1159/000363006

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