Comparison of qSOFA, SIRS, NEWS and REWS Scores in Predicting Severity and 28-day Mortality of older Suspected Sepsis Cases; a Prognostic Accuracy Study.

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qSOFA score ≥2 was superior to SIRS ≥2, NEWS ≥5, and REWS ≥4 in predicting 28-day mortality and septic shock in elderly patients with suspected sepsis in the ED. However, the predictive performance of qSOFA ≥2 was only moderate (AUC<0.8). Therefore, to reduce mortality and improve outcomes, we suggest the use of qSOFA ≥2 combined with clinical or other early warning scores, or the development of new prediction scores for screening, triage, and prediction of mortality and of severity of sepsis in elderly patients with suspected sepsis in the ED.