In vitro study demonstrates reversible switching of magnesium-dependent DNAzyme activity using metal ion complexes, indicating versatile mechanisms for responsive catalytic DNA nanodevices.
The activities of Mg(2+)-dependent DNAzymes are reversibly switched by ion stimuli using the thymine-Hg(2+)-thymine complexes or cytosine-Ag(+)-cytosine complexes.
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Shimron et al. (2010) studied this question.
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