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January 17, 2014American Journal of Psychiatry687 citationsOpen Access

Comprehensive Meta-Analysis of Excess Mortality in Depression in the General Community Versus Patients With Specific Illnesses

PCPim CuijpersNVNicole VogelzangsJTJos W. R. Twisk

Structured PICO

Is depression associated with excess mortality in the general community versus patients with specific illnesses?

P
Population
General community and patients with specific illnesses
I
Intervention
Depression
O
Outcome
Excess mortalityhard clinical

This meta-analysis confirms a significant association between depression and excess mortality, while highlighting that publication bias and low study quality may lead to overestimation.

Limitations

  • publication bias
  • low study quality

Abstract

The authors could confirm the presence of a significant association between depression and excess mortality, although this association may have been overestimated because of publication bias and low study quality. Few indications were found that this association is stronger in community or specific patient samples.

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Cite This Study

Cuijpers et al. (2014) studied this question.

synapsesocial.com/papers/69db22a64a1e15904c837013https://doi.org/10.1176/appi.ajp.2013.13030325
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