Why the study?
Does insulin increase capillary recruitment and alter blood flow distribution in rat skeletal muscle?
Population
Anesthetized rats
Comparison
Euglycemic insulin clamp (10 mU x min x kg[-1]) vs Control animals and epinephrine infusion (0.125…
Design
Preclinical
Authors
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Insulin-specific capillary recruitment in rat muscle is not flow-dependent; leaves open translation to human insulin resistance and glucose disposal.
Does insulin increase capillary recruitment and alter blood flow distribution in rat skeletal muscle?
Insulin increases total hind leg blood flow and capillary recruitment in rat skeletal muscle, an effect not mimicked by epinephrine.
Rattigan et al. (1997) studied this question.