Does EDIL3 deficiency ameliorate adverse cardiac remodelling after myocardial infarction?
EDIL3 deficiency reduces adverse cardiac remodeling after myocardial infarction by modulating neutrophil-macrophage crosstalk.
We not only reveal that EDIL3 deficiency ameliorates adverse cardiac healing via NET-mediated pro-inflammatory macrophage polarization but also discover a new crosstalk between neutrophil and macrophage after MI.
Wei et al. (Sun,) studied this question.