Treatment of Intrabony Defects Using Guided Tissue Regeneration or Enamel Matrix Derivative: A 3‐Year Prospective Randomized Clinical Study

The treatment of intrabony defects in patients with chronic advanced periodontitis using GTR or EMD led to significantly improved clinical parameters. Tests of statistical significance demonstrated better results with EMD, although the absolute differences between treatment modalities was small. Further studies with a larger number of treated defects are necessary to verify these findings.