Linezolid-Induced Optic Neuritis in Tuberculosis: A Systematic Review of Case Reports, Case Series, and Cohort Studies | Synapse
April 12, 2026Open Access
Linezolid-Induced Optic Neuritis in Tuberculosis: A Systematic Review of Case Reports, Case Series, and Cohort Studies
Key Points
To examine the occurrence and implications of linezolid-induced optic neuritis in tuberculosis patients.
Conducted a systematic review of case reports, case series, and cohort studies.
Analyzed patient outcomes related to optic neuritis caused by linezolid.
Evaluated the effectiveness of drug withdrawal and monitoring strategies.
Optic neuritis is identified as a rare but significant side effect of linezolid.
Early recognition and prompt drug withdrawal are crucial for patient recovery.
Routine ophthalmological monitoring is recommended for patients receiving linezolid.
Abstract
This is an infrequent but clinically significant complication that requires early recognition, prompt drug withdrawal, and routine ophthalmological monitoring.