Exploration of the relationship between miR-146a rs2910164 polymorphisms and the efficacy of epidural fentanyl in labor analgesia among pregnant women

Key Points

• This research investigates the link between miR-146a polymorphisms and the effectiveness of epidural fentanyl analgesia during labor.
• Genetic association study focusing on rs2910164 polymorphisms
• Assessment of epidural fentanyl efficacy
• Comparison of CC genotype with other genotypes
• CC genotype at the rs2910164 locus linked to reduced efficacy of epidural fentanyl
• Need for further validation in larger multicenter studies