RBM24 plays a critical role in cardiac development by regulating alternative splicing of core myofibrillogenesis genes to orchestrate sarcomere organization.
RBM24 modulation merits study in cardiomyopathy models; leaves open translation to patients.
RBM24 acts as a master regulator to modulate the temporal dynamics of core myofibrillogenesis genes and thereby orchestrates sarcomere organization.
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Lu et al. (2021) studied this question.
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