What are the different risk factors for early versus late colorectal anastomotic leakage?
Early anastomotic leakage is primarily driven by surgical difficulty, while late leakage is driven by patient frailty and tissue healing deficiencies.
Most risk factors for early anastomotic leakage were surgery-related factors, representing surgical difficulty, which might lead to technical failure of the anastomosis. Most risk factors for late anastomotic leakage were patient-related factors, representing the frailty of patients and tissues, which might imply healing deficiencies. See Video Abstract at http://links.lww.com/DCR/A730.
Sparreboom et al. (Thu,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: