[reaction: see text] Acid-catalyzed condensation of aromatic amines with delta,epsilon-unsaturated aldehydes, followed by intramolecular formal hetero Diels-Alder reaction, is described as a potential route to the cyclopenta[b]quinoline substructure of isoschizozygane alkaloids. Reactions are highly diastereoselective and produce adducts with up to four contiguous stereocenters.
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Nabi A. Magomedov (2003) studied this question.
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