Why the study?
Does higher serum fasting insulin and insulin resistance predict cognitive decline in an adult population?
Does higher serum fasting insulin and insulin resistance predict cognitive decline in an adult population?
Higher fasting insulin and insulin resistance are associated with steeper cognitive decline over 11 years, suggesting that preventing or treating insulin resistance may help preserve cognitive function.
Associated with steeper verbal fluency decline; hypothesis-generating for whether targeting insulin resistance slows cognitive loss.
Our results show that higher serum fasting insulin and insulin resistance predict poorer verbal fluency and a steeper decline in verbal fluency during 11 years in a representative sample of an adult population. Prevention and treatment of insulin resistance might help reduce cognitive decline later in life.
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Ekblad et al. (2017) studied this question.
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