Asini Corii Colla (Ejiao) is recognized as an excellent source that bridges both medicinal and nutritional benefits. It is rich in protein, polypeptides, amino acids, fatty acids, polysaccharides, and other components. It offers a range of therapeutic benefits, including anti-anemia properties, immune regulation, hemostasis, anti-inflammatory effects, antioxidant activity, and antibacterial properties. Beyond its medicinal uses, the food industry uses Asini Corii Colla to produce foods like Ejiao cake and Ejiao porridge, which are both delicious and nutritious and promote health, making them popular among consumers. This review aims to provide comprehensive data on the chemical composition, pharmacological activity, quality control, and modern applications of Asini Corii Colla. Additionally, it addresses current research gaps and suggests future directions and methodologies for studying food and medicine derived from animal sources to guide subsequent research and applications. • The chemical composition, pharmacological effects, quality standards, and applications of ACC, guiding future research. • Identifies bioactive components, highlighting their pharmacological significance. • Proposes a spectrum-efficacy correlation strategy based on pseudo-targeted peptidomics to identify bioactive components.
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Yu et al. (2025) studied this question.
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