Why the study?
Does severe carotid stenosis and associated hemodynamic impairment increase the risk of cognitive deterioration in asymptomatic subjects?
Does severe carotid stenosis and associated hemodynamic impairment increase the risk of cognitive deterioration in asymptomatic subjects?
Severe carotid stenosis, particularly when accompanied by hemodynamic impairment, is associated with an increased risk of cognitive deterioration in asymptomatic patients.
Highlights need for cognitive assessment in asymptomatic severe carotid stenosis; leaves open whether correcting hemodynamic impairment prevents decline.
Our findings show that the presence of a severe carotid stenosis influences cognitive deterioration over a 36-month period in asymptomatic subjects. An associated hemodynamic impairment significantly increases the risk. Evaluation of functional consequences of carotid stenosis may offer the opportunity to select a group with an increased risk of developing cognitive impairment from subjects with asymptomatic severe carotid stenosis.
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Balestrini et al. (2013) studied this question.
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