Despite high measures of reliability for the various methods reported in current studies, there is vast disagreement regarding the actual values of the slope that would be considered "at risk." Reported tibial slope values for control groups vary greatly between studies. In many cases, the study-to-study differences in "normal" tibial slope exceed the difference between controls and ACL-injured patients. The clinical utility of imaging-based measurement methods for the determination of ACL injury risk requires more reliable techniques that demonstrate consistency between studies.
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Wordeman et al. (2012) studied this question.