We first discuss several key technical issues associated with quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), and then provide examples of DCE-MRI in oncology. In particular, we examine the importance of both active and passive delivery of the contrast agent to the tissue under investigation, and repeatability/reproducibility in DCE-MRI studies. We then discuss examples of how DCE-MRI can assist in assessing and predicting therapeutic response in the neoadjuvant setting.
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Barnes et al. (2014) studied this question.
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